BIOT 101 Introduction to Good Manufacturing Practices (GMP) (Cr3) (3:0)
Course is designed to give an overview of biomanufacturing processes and the fundamentals of current Good Manufacturing Practice (GMP) in the field of sterile products and aseptic processing. A significant portion of the course will be geared towards understanding the latest US Food and Drug Administration's guidance documents and their applications. The course will also introduce the student to the European version of current GMP. Also available through Online Learning.
BIOT 120 Cleanroom Microbiology (Cr2) (1:2)
Course presents the basic information on cleanroom operations and management. Content will focus on basics of cleanroom design, daily operation and cleaning, understanding how a cleanroom can become contaminated, microbial monitoring, determining the source of contamination, identification of the contaminant, disinfection processes and prevention of recontamination. All techniques will be in accordance with procedures outlined by the International Standards Organization (ISO) and the International Association for Pharmaceutical Science and Technology (ISPST). Pre- or coreq.- BIOT 184 or permission of the instructor.
BIOT 175 Introduction to Biomanufacturing (Cr4) (3:3)
This course presents fundamentals of Biomanufacturing or a type of manufacturing that utilizes biological systems to produce commercially important products. Biomanufactured products range from biopharmaceuticals to industrial enzymes, human tissues and replacement organs, biofuels, "green" chemicals, and the green products replacing those derived from petroleum. Students will be introduced to the different bioprocessing methods including a survey of proteins and vaccines currently produced by biopharmaceutical companies. Content of the course emphasizes complexity of the processing approaches, methods for the effective environmental monitoring and control presented in the context of regulatory compliance. Regulatory environment of the industry Good Manufacturing Practices (GMP's) and the current thinking of the United States Food and Drug Administration (FDA) will be discussed.
BIOT 184 Introduction to Biotechnology (Cr4) (3:2)
This course introduces the fundamental scientific concepts of biotechnology. The course covers historical development in the field and current applications in the areas of agriculture, medicine, forensics, environment, renewable energy, and chemical industry. The scientific basis of recombinant DNA technology, cell culture, stem cells, cloning, bio-terrorism, vaccines, bioethics, and other current developments are explained. The laboratory component of the course reinforces the scientific inquiry method. Pre- or coreq.- BIOS 107. Also available through Online Learning.
BIOT 185 Biotechnology Techniques (Cr4) (3:3)
Concepts and techniques necessary to work effectively in a biotechnology research or manufacturing laboratory. The importance of quality regulations and standards and the role of the technician in producing quality results will be emphasized. Students will gain theoretical and practical knowledge of laboratory instruments as well as basic laboratory techniques. Topics will include maintenance, record keeping, cleaning and calibration of laboratory equipment, preparation of common solutions and reagents, and writing and following procedures. Computer software will be used to generate spreadsheets and data analysis. Applications of bio-separations, cell culture, and fermentation will be introduced. Students will be trained in laboratory safety policies and good laboratory practices (GLP). Prereq. - BIOS 107 and CHEM 120.
BIOT 188 Biotechnology Internship (Cr1) (0:0:varies)
Work experience in the biotechnology/pharmaceutical industry or other related industries. Prereq. - BIOT 185.
BIOT 202 Biotechnology Seminar (Cr1) (1:0)
This course is designed to do a survey (in seminar format) of current advances in biotechnology, bioinformatics, and the societal implications of biotechnological developments. Students will develop the presentation and discussion skills necessary for a biotechnology career by giving oral presentations on these topics and participating in instructor-facilitated group discussions. The importance of using current journals, scientific meetings, and the internet to stay current in biotechnological topics will be emphasized. Prereq. - BIOS240 and CMTH102.
BIOT 220 General Biotechnology (Cr4) (3:3)
This course is designed to provide a survey of biotechnological applications of molecular and cell biology. Topics include transcription, translation, cell cycle regulation, protein expression, prokaryotic and eukaryotic expression systems, DNA sequencing and amplification. The laboratory will give the students exposure to recombinant DNA technology such as cloning techniques, restriction digests, DNA isolation and purification, electrophoresis, DNA amplification and analysis protein expression and purification, and immunoassays. This course will concentrate on the molecular principles of biotechnology related to broad range of applications. Its objective is to build skills necessary for successful employment in biopharmaceutical industry or transfer into four year academic institution. Prereq. - BIOT175 and BIOS240.